The wisdom suggests that if your life does depend on an outdated drug, and you must have 100% of the original strength, it is wise to follow the cliché "better safe than sorry".
According to The Medical Letter (2015) the only report of human toxicity that may have been caused by chemical or physical degradation of a pharmaceutical product is renal tubular damage that was associated with use of degraded tetracycline (GW Frimpter et al, JAMA 1963; 11).
Updated: April, 2017 Many medications are very expensive and people hate to waste them.
To avoid a costly visit to the doctor for a new prescription, many people have to consume expired drugs.
Physicians and pharmaceutical companies, because of legal restrictions and liability concerns, will not sanction such use and may not even comment on the safety or effectiveness of using their products beyond the date on the label. The expiration date, required by law in the United States, beginning in 1979, indicated the date the manufacturer guarantees the full potency and safety of the drug.
At the time of the medication expiry date, the drug must be at least 90% of the original potency under proper storage conditions.